Her Manic Pixie Dream Girl schtick jumped the shark somewhere around five years ago. Putting her in a middling sitcom instead of a shitty movie doesn't make it any better.
I don't care if somebody is offensive or a pervert, so long as they're funny about it. Being unoriginal, cliche or uninspired is reason enough for the banhammer, moralizing be damned.
Personally, I'd pick West Virginia. South Carolina's my sleeper pick (although I love Charleston). But if I had to put money down, I'd say Arizona. SB 1070 was bad enough on its own, but then you've got the murderer's row of Joe Arpaio, John McCain and Jared Loughner.
Outside of the Keys, South Florida is a hellhole. And the natural beauty of northern FL more than makes up for the fact that it's essentially South Georgia, IMHO.