It was a 4-4 game until Orioles left fielder Austin Hays drove in shortstop Jorge Mateo with a single in the bottom of the fifth. Hays collected two of Baltimore's 13 hits
Rafael Devers hit his American League-leading ninth home run of the season for Boston, which received a solo home run from Triston Casas and three hits from Masataka Yoshida.
After committing a balk that allowed pinch runner Raimel Tapia to take second base with no one out in the ninth, Baltimore reliever Yennier Cano retired the next three batters in order to record the save, his first of the season.
Baltimore starter Dean Kremer (2-0) allowed four runs on seven hits in 5 2/3 innings. He struck out five and walked one.
Boston received five innings from Chris Sale (1-2), who surrendered five runs on nine hits. He walked one and didn't record a strikeout.
After Casas opened the scoring with his home run in the second, the Red Sox took a 2-0 lead in the third when an Alex Verdugo single scored Connor Wong. Devers followed with a two-run homer to raise Boston's lead to 4-0
The Orioles got on the scoreboard in their half of the third, when Adam Frazier singled home Cedric Mullins. Baltimore tied the game in the fourth when a Ramon Urias double scored Ryan Mountcastle and Anthony Santander, and then Urias scored on a James McCann single
Urias had two hits and drove in two runs for the Orioles. Mountcastle and Mullins also had two hits apiece for Baltimore
--Field Level Media