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Brock Purdy's 5-TD night powers 49ers past Colts
Brock Purdy threw a career-high five touchdown passes, two to running back Christian McCaffrey, and the San Francisco 49ers remained in the thick of the NFC West title chase with a 48-27 road victory over the Indianapolis Colts on Monday night.,McCaffrey rushed for 117 yards and hauled in TD passes ...

Week 16 MNF: 49ers-Colts Preview, Props, Prediction
Several NFL teams will be watching in earnest when the San Francisco 49ers travel to take on the Indianapolis Colts on Monday night in a game chock full of playoff implications for both conferences to close out Week 16.,The 49ers (10-4) have clinched a playoff spot, but they also sit in third place ...

49ers, Colts not ready to abandon division-title hopes
Having had an opportunity to watch division rivals attempt to hold serve in a tight playoff race, the San Francisco 49ers and Indianapolis Colts get a chance to help themselves on the field when they clash Monday night in Indianapolis.,The 49ers (10-4) sit in third place in the NFC West, looking up ...

49ers knock off Titans for fourth straight win
Brock Purdy threw three touchdown passes, two to Jauan Jennings, Christian McCaffrey rushed for 73 yards and a score, and the San Francisco 49ers outlasted the visiting Tennessee Titans 37-24 in Santa Clara, Calif., on Sunday afternoon for a fourth straight win.,George Kittle had eight catches for 8...

49ers standout RB Christian McCaffrey (back) added to injury report
San Francisco 49ers star running back Christian McCaffrey was added to the team's injury report Saturday due to a back injury.,McCaffrey was listed as questionable for Sunday's game against the visiting Tennessee Titans. Despite the status designation, ESPN reported that McCaffrey is expected to pla...

Cam Ward, Brock Purdy face off as Niners host Titans
Two quarterbacks at the opposite end of the draft spectrum go head-to-head for the first time when Cam Ward and the Tennessee Titans visit Brock Purdy and the San Francisco 49ers on Sunday afternoon in Santa Clara, Calif.,The game matches teams coming off wins in Cleveland a week apart, with the Tit...

Jags turn up heat in South, lean into decade-long streak vs. Colts
First place in the AFC South is the imaginary trophy on the line Sunday when the Jacksonville Jaguars and Indianapolis Colts square off for one of their two meetings in the next 21 days. ,There is nothing invisible about the mounting pressure on Indianapolis (8-4) to regenerate positive momentum wit...

Titans fight Browns to escape Land of the Lost
Draft talk is top of mind for the Tennessee Titans as they touch down in Cleveland with a 1-17 record in their past 18 games and with an active seven-game losing streak.,Even at 3-9, the Cleveland Browns enter the Sunday visit from the Titans mathematically eligible for the AFC playoffs. However, th...

49ers LG Ben Bartch (foot) likely done for season
San Francisco 49ers left guard Ben Bartch is headed to injured reserve with a sprained foot and likely done for the season, head coach Kyle Shanahan confirmed.,Bartch was injured Sunday at Cleveland as the 49ers (9-4) earned their third straight win with a 26-8 victory against the Browns.,Also hurt ...

49ers take advantage of Browns miscues in comfortable win
Brock Purdy passed for a touchdown and ran for another as the visiting San Francisco 49ers extended their winning streak to three games by beating the Cleveland Browns 26-8 Sunday.,Purdy completed 16 of 29 passes for 168 yards. Christian McCaffery added a 1-yard TD run for San Francisco (9-4), which...

No. 24 Tulane shuts out Charlotte, advances to American title game
Tulane did its damage early by finding paydirt on its first two drives, and the No. 24 Green Wave locked in a spot in the American Conference title game by blanking the Charlotte 49ers 27-0 on Saturday night in New Orleans, La.,With the win, the Green Wave (10-2, 7-1) earned the right to host North ...

49ers focused on limiting damage by Browns' Myles Garrett
Two defenses coming off impressive performances set their targets on history-defying young quarterbacks when the San Francisco 49ers visit the Cleveland Browns on Sunday afternoon.,Brock Purdy will be looking for a third consecutive victory, while Shedeur Sanders will be seeking to deliver the Brown...
NFC West Power Rankings: Rams Lead the Pack in Week 13
The NFC West is tighter than ever in Week 13, but the Los Angeles Rams’ 9-2 record, MVP-caliber Matthew Stafford, and league-leading defense put them ahead of the Seahawks and 49ers....

49ers overcome Brock Purdy's picks, shut down Panthers
Christian McCaffrey ran for 89 yards and a touchdown and the San Francisco 49ers overcame a horrible first-half stretch from quarterback Brock Purdy to beat the Carolina Panthers 20-9 on Monday night in Santa Clara, Calif.,The 49ers (8-4) did the job on defense to register back-to-back wins for the ...

Week 12 MNF: Panthers-49ers Preview, Props, Prediction
Week 12 of the regular season closes with an intriguing matchup between a surprising team seeking a statement road win against a franchise trying to prove it still belongs among the NFL's top tier of contenders.,Carolina (6-5) has won five of its past seven games, and a win on Monday night would vau...

Report: 49ers void Brandon Aiyuk's 2026 guarantees
The San Francisco 49ers voided the guaranteed money in wide receiver Brandon Aiyuk's contract for 2026 during training camp, multiple outlets reported.,Aiyuk, who has not played since sustaining a knee injury in October 2024, had not been meeting the requirements of his deal, per Friday's reports.,S...

Panthers ready for rare big game on Monday night vs. 49ers
Without many opportunities for what would qualify as a significant game in recent seasons, this is about as big as it gets for the Carolina Panthers.,The San Francisco 49ers are more accustomed to these assignments.,Monday night's matchup between the teams at Santa Clara, Calif., could have ramifica...

Bears at Packers flexed to later start, Bills-Bengals early in Week 14 swap
Traditional NFC North rivals were bumped closer to primetime with the NFL adjusting the Dec. 7 schedule to feature the Chicago Bears and Green Bay Packers at Lambeau Field in the late afternoon slot. ,The game will replace the Cincinnati Bengals-Buffalo Bills matchup, which rolls forward to a 1 p.m....

49ers top Cardinals in Brock Purdy's return despite Jacoby Brissett's record day
Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three touchdowns and the San Francisco 49ers beat the error-prone Arizona Cardinals 41-22 on Sunday in Glendale, Ariz.,Purdy completed 19 of 26 passes without an interception in his ret...

Brock Purdy back under center for 49ers at Cardinals
San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday in Phoenix.,The 49ers (6-4) will have Brock Purdy back under center as they go for a series sweep and push for their fourth playoff appearance in five seasons.,Purdy returned ...