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49ers overcome Brock Purdy's picks, shut down Panthers
Christian McCaffrey ran for 89 yards and a touchdown and the San Francisco 49ers overcame a horrible first-half stretch from quarterback Brock Purdy to beat the Carolina Panthers 20-9 on Monday night in Santa Clara, Calif.,The 49ers (8-4) did the job on defense to register back-to-back wins for the ...

Week 12 MNF: Panthers-49ers Preview, Props, Prediction
Week 12 of the regular season closes with an intriguing matchup between a surprising team seeking a statement road win against a franchise trying to prove it still belongs among the NFL's top tier of contenders.,Carolina (6-5) has won five of its past seven games, and a win on Monday night would vau...

Report: 49ers void Brandon Aiyuk's 2026 guarantees
The San Francisco 49ers voided the guaranteed money in wide receiver Brandon Aiyuk's contract for 2026 during training camp, multiple outlets reported.,Aiyuk, who has not played since sustaining a knee injury in October 2024, had not been meeting the requirements of his deal, per Friday's reports.,S...

Panthers ready for rare big game on Monday night vs. 49ers
Without many opportunities for what would qualify as a significant game in recent seasons, this is about as big as it gets for the Carolina Panthers.,The San Francisco 49ers are more accustomed to these assignments.,Monday night's matchup between the teams at Santa Clara, Calif., could have ramifica...

49ers top Cardinals in Brock Purdy's return despite Jacoby Brissett's record day
Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three touchdowns and the San Francisco 49ers beat the error-prone Arizona Cardinals 41-22 on Sunday in Glendale, Ariz.,Purdy completed 19 of 26 passes without an interception in his ret...

Brock Purdy back under center for 49ers at Cardinals
San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday in Phoenix.,The 49ers (6-4) will have Brock Purdy back under center as they go for a series sweep and push for their fourth playoff appearance in five seasons.,Purdy returned ...

Brock Purdy may be back under center for 49ers at Cardinals
San Francisco and Arizona are in separate stages of quarterback drama as they prepare to conclude their season series Sunday in Phoenix.,The 49ers (6-4) likely will have a choice between Brock Purdy and fill-in Mac Jones as they go for a series sweep and push for their fourth playoff appearance in f...

49ers QB Brock Purdy could return to starting role vs. Cardinals
The San Francisco 49ers plan to push Brock Purdy aggressively in practice this week with the hope he will start Sunday's road game against the Arizona Cardinals.,Purdy last played in Week 4 when he aggravated a toe injury during a loss to the Jacksonville Jaguars. He initially hurt the toe in the se...

Matthew Stafford tosses 4 more TDs, high-scoring Rams top 49ers
Matthew Stafford threw four touchdown passes, Kyren Williams rushed for two scores and the Los Angeles Rams avenged one of their two defeats with a 42-26 victory over the San Francisco 49ers on Sunday in Santa Clara, Calif.,Davante Adams and Puka Nacua caught touchdown passes as the Rams (7-2) exten...

49ers place DE Mykel Williams (knee) on IR, activate G Ben Bartch
The San Francisco 49ers placed rookie defensive end Mykel Williams on injured reserve on Saturday.,Williams suffered a season-ending torn ACL last Sunday in a 34-24 win over the host New York Giants.,In other moves on Saturday, the 49ers activated guard Ben Bartch from the IR and elevated defensive ...

Rejuvenated Matthew Stafford, Rams ready for rivalry game vs. 49ers
A storied rivalry will add another significant chapter Sunday afternoon when the San Francisco 49ers stare down the Los Angeles Rams at Santa Clara, Calif.,The NFC West foes intend to stand out on top of a conference crowded with contenders. The Rams (6-2) are one of four teams tied for the best rec...

Christian McCaffrey breaks NFL record as 49ers handle Giants
Christian McCaffrey totaled 173 yards and had a pair of touchdowns, Mac Jones threw for a pair of first-half scores and the San Francisco 49ers earned a 34-24 victory over the New York Giants Sunday afternoon in East Rutherford, N.J.,McCaffrey gained 106 yards on the ground after being held to a sea...

49ers' Brock Purdy (toe) questionable, but Mac Jones starting vs. Giants
San Francisco 49ers quarterback Brock Purdy is listed as questionable for Sunday's game against the New York Giants but Mac Jones will once again draw the start.,San Francisco coach Kyle Shanahan made the announcement Friday afternoon that Jones will start while indicating Purdy (toe) has made progr...

Rested Rams ready for rookie QB, Saints
Ready or not, Tyler Shough, the Los Angeles Rams are waiting.,Saints coach Kellen Moore broke the glass in Week 8, bringing rookie second-round pick Shough off the bench in relief of starting quarterback Spencer Rattler last week in a loss to the Buccaneers that dropped New Orleans to 1-7. ,"Tyler's...

49ers’ top priority is running roughshod over Giants
The San Francisco 49ers may find a cure for their ailing running game when they meet the New York Giants on Sunday in East Rutherford, N.J.,The 49ers (5-3) rank last in the NFL with 3.4 yards per carry this season, while the Giants (2-6) are giving up a league-high 5.7 yards per carry. San Francisco...

Reports: Patriots trade S Kyle Dugger to Steelers, DE Keion White to 49ers
The New England Patriots moved on from a pair of former defensive starters on Tuesday by trading safety Kyle Dugger to the Pittsburgh Steelers and defensive end Keion White to the San Francisco 49ers, according to multiple media reports.,Both swaps are framed the same: The Patriots are sending a sev...

C.J. Stroud shines with 318 yards, 2 TDs in Texans’ win over 49ers
C.J. Stroud threw for season-high 318 yards and two touchdowns as the host Houston Texans never trailed and turned in their best offensive showing of the season in a 26-15 victory over the San Francisco 49ers on Sunday afternoon.,Stroud completed 30 of 39 passes to nine different players for his nin...

Mac Jones to start vs. Texans, Brock Purdy out again
Mac Jones will again be the starting quarterback for the San Francisco 49ers after Brock Purdy was ruled out of Sunday's game against the Houston Texans due to his toe injury.,It will mark the fourth straight game and sixth overall that Purdy has missed this season. He was injured in a Week 1 victor...

John Lynch: 49ers' Brock Purdy, Brandon Aiyuk getting closer
San Francisco 49ers quarterback Brock Purdy's season to date has largely been derailed by a toe injury.,He sustained the injury in Week 1, returned in Week 4 but has missed the last three games after dealing with a setback in his recovery.,Real details about a possible timeline for return to action ...

C.J. Stroud, Texans confident heading into meeting with injury-ravaged 49ers
A three-team tussle atop the NFC West figures to naturally play itself out by season's end.,While the San Francisco 49ers have gained an early edge with victories against fellow 5-2 rivals Los Angeles and Seattle, right tackle Colton McKivitz knows a Week 8 visit to Houston offers a unique challenge...