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49ers RB Christian McCaffrey (knee) potentially out for season
San Francisco 49ers star running back Christian McCaffrey's season is in jeopardy after he sustained what is believed to be a posterior cruciate ligament injury in Sunday's 35-10 loss to the Buffalo Bills in Orchard Park, N.Y. ,"I think potentially (it's season-ending)," 49ers head coach Kyle Shanah...

Josh Allen makes TD history as Bills stomp on 49ers
Josh Allen became the first quarterback since 1970 to score a rushing touchdown, pass for a touchdown and have a scoring reception in the same game and the Buffalo Bills clinched the AFC East for the fifth consecutive season with a convincing 35-10 victory over the San Francisco 49ers on Sunday nigh...

49ers star RB Christian McCaffrey leaves game with knee injury
San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early in the second quarter due to a knee injury.,The 49ers originally listed McCaffrey as questionable to return shortly after he left the playing surface for further examination. H...

QB Brock Purdy active for 49ers against Bills
San Francisco quarterback Brock Purdy, after missing one game because of an ailing right shoulder, will start for the 49ers on Sunday night against the host Buffalo Bills.,Purdy was listed as questionable after being limited at practice Wednesday and Thursday but was a full participant on Friday and...

Banged-up 49ers hope to get well against soaring Bills
The Buffalo Bills might have a chance to clinch the AFC East on Sunday night when they battle the injury-decimated San Francisco 49ers at Orchard Park, N.Y.,Buffalo (9-2) has won six straight games and is on the verge of a fifth straight AFC East crown. If the Miami Dolphins lose to the Green Bay Pa...

Injuries pile up, 49ers uncertain QB Brock Purdy can return Sunday
San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there is growing concern about the long-term status of left tackle Trent Williams. ,Wednesday's practice was not the start to the NFL workweek head coach Kyle Shanahan had hoped af...

Josh Jacobs, Packers roll over banged-up 49ers
Josh Jacobs rushed for 106 yards and three touchdowns and the defense forced three turnovers to lift the host Green Bay Packers to a 38-10 rout of the slumping San Francisco 49ers on Sunday.,Green Bay (8-3) avenged last season's playoff defeat to the reigning NFC champion 49ers, who lost their secon...

Not Purdy: 49ers hit Green Bay with backup QB, no Nick Bosa
Quarterback Brock Purdy and defensive end Nick Bosa are not available for the San Francisco 49ers as they enter Green Bay with designs on finding their finishing kick on Sunday afternoon.,Purdy is out with a right shoulder injury and won't leave the sideline at Lambeau Field, head coach Kyle Shanaha...

Not Purdy: 49ers hit Green Bay with backup QB, no Bosa
Brock Purdy and Nick Bosa are not available for the San Francisco 49ers when they enter Green Bay with designs on finding their finishing kick on Sunday afternoon.,Purdy is out with a right shoulder injury and won't leave the sideline at Lambeau Field, head coach Kyle Shanahan said Friday, when he a...

49ers QB Brock Purdy, DE Nick Bosa out, Brandon Allen to start at Green Bay
San Francisco 49ers quarterback Brock Purdy will not play Sunday and head coach Kyle Shanahan said the lingering discomfort is a concern.,Purdy sat out Friday after he participated in the start of Thursday's practice with the 49ers, then retreated indoors for what Shanahan said was a treatment sessi...

Limited again, 49ers QB Brock Purdy still fighting sore shoulder
Brock Purdy participated in the start of Thursday's practice with the 49ers but the San Francisco starting quarterback was not on the field for the majority of the workout, casting doubt over his availability to play Sunday at Green Bay. ,Purdy is dealing with a right shoulder injury and the 49ers a...

49ers hit Green Bay with Packers in pursuit of NFC leaders
A victory against the visiting San Francisco 49ers on Sunday would bolster the Green Bay Packers' playoff chances, send a conference rival below .500 and avenge a bitter playoff defeat.,Those seemingly rank in no particular order for the Packers (8-3), although they don't shy from living at least pa...

49ers consider QB Brock Purdy (shoulder) day-to-day
The injury-prone San Francisco 49ers are monitoring yet another health issue, this one involving quarterback Brock Purdy's right shoulder.,Coach Kyle Shanahan said on Monday that Purdy emerged from the team's 20-17 home loss to the Seattle Seahawks a day earlier with a sore throwing shoulder. Purdy ...

49ers star DE Nick Bosa aggravates hip, injures other hip
San Francisco 49ers All-Pro defensive end Nick Bosa aggravated a hip injury and hurt his other hip in the process during Sunday's 20-17 home loss to the Seattle Seahawks.,Bosa, 27, had dealt with a hip issue leading up to the game and was listed as questionable, but suited up and finished with 1 1/2...

Geno Smith's late TD run lifts Seahawks over 49ers
Geno Smith scored on a 13-yard scramble with 12 seconds remaining as the Seattle Seahawks upended the host San Francisco 49ers 20-17 Sunday afternoon in Santa Clara, Calif.,The Seahawks (5-5), who were coming off their bye week, snapped a two-game skid and won for just the second time in their past ...

Stipe Miocic to retire after loss to Jon Jones
Former UFC heavyweight champion Stipe Miocic is retiring.,"I'm done," Miocic said after losing to Jon Jones at UFC 309 Saturday night in New York. "I'm hanging ‘em up. I'm retiring.",Miocic lost in a third-round stoppage after he took blows to the head and a spinning back kid to the ribs. He retires...

49ers TE George Kittle expected to sit vs. Seahawks
San Francisco 49ers tight end George Kittle plans to test his injured hamstring prior to Sunday's game against the visiting Seattle Seahawks, but multiple reports indicate he'll be sidelined for the Week 11 game. ,Kittle felt discomfort in the hamstring earlier in the week. Head coach Kyle Shanahan ...

Jon Jones keeps heavyweight belt at UFC 309
Jon Jones defended his heavyweight title during the main event at UFC 309 in New York on Saturday night, using a spinning back kick to beat Stipe Miocic by technical knockout. ,The bout was called at 4:29 of the third round. ,It was Jones' first fight since March 2023, and the 37-year-old successful...
Nine Reasons Why the San Francisco 49ers Won’t Be Going Back to the Super Bowl
At 5-4, the San Francisco 49ers don't have to worry about going back to the Super Bowl in New Orleans this February. Here are nine reasons why....

Jon Jones, Stipe Miocic end layoffs with UFC 309 clash
Jon Jones returns to the Octagon for the first time in 20 months when he puts his heavyweight title on the line against Stipe Miocic in UFC 309 on Saturday in New York.,Jones (27-1 MMA) last fought in March 2023, when he won the then-vacant heavyweight title against Ciryl Gane with a first-round sub...