Mac Jones to start vs. Texans, Brock Purdy out again
Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) after the game against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images Mac Jones will again be the starting quarterback for the San Francisco 49ers after Brock Purdy was ruled out of Sunday's game against the Houston Texans due to his toe injury.
It will mark the fourth straight game and sixth overall that Purdy has missed this season. He was injured in a Week 1 victory over the Seattle Seahawks and aggravated the toe during a Week 4 loss to the Jacksonville Jaguars.
San Francisco is 4-1 when Jones starts this season. He has passed for 1,404 yards, six touchdowns and four interceptions.
Receiver Ricky Pearsall (knee) will miss his fourth straight game. Also ruled out on Friday were center Jake Brendel (hamstring) and defensive ends Bryce Huff (hamstring) and Yetur Gross-Matos (knee/hamstring).
Cornerback Deommodore Lenoir (quadriceps), linebacker Luke Gifford (hamstring) and offensive lineman Spencer Burford (knee) are questionable.
--Field Level Media
- World Series Game 5 Betting Picks: Blue Jays vs. Dodgers Player Props
- NBA Best Bets for October 28th: Expert Picks for Tuesday
- World Series Game 4 Best Bets: October 28th's Top Props and Picks
- World Series Game 3 Betting Picks: Blue Jays vs. Dodgers Player Props & Totals
- NBA Best Bets Oct. 27th: Hawks vs Bulls, Raptors vs Spurs, Suns vs Jazz Picks
- Commanders vs. Chiefs Week 8 Monday Night Football Top Betting Picks, Predictions
- Top 10 NFL Week 8 Player Props and Best Bets for Sunday’s Slate