Lions vs. Chiefs Sunday Night Football Week 6 Betting Predictions

The Detroit Lions get a road matchup against the Kansas City Chiefs on Sunday Night Football for Week 6. The Lions have looked dominant in recent weeks, rattling off four consecutive wins after losing their opening game against the Green Bay Packers. The Chiefs have struggled a bit early, posting a 2-3 record through five games.

Detroit struggled to move the ball against the Green Bay Packers in Week 1, but they’ve been a dominant offense since. Through five games, they lead the NFL in points (.569) per play. They’re also averaging a league-high 34.8 points per game.

The Lions have been one of the best offenses in the NFL once they get to the red zone. They’re converting 76% of their red zone drives into touchdowns this season. That number’s up to 85.7% over their last three games.

The Chiefs haven’t been a bad defense in 2025, but they also haven’t been elite. They rank 16th in points allowed (.372) per play. They’re also allowing their opponents to score a touchdown on 60% of their red zone drives this season.

Detroit’s going to score points in this game, which leads us to determine how much offensive success Kansas City will have. It hasn’t been the best start for their offense, ranking 17th in the NFL in points (.397) per play. They are averaging 25 points per game, though.

This is a different offense with Xavier Worthy playing, even if he isn’t fully healthy. He’s played in each of their last two games, and they’re averaging 32.5 points per game in those contests. They topped out at 37 points against the Baltimore Ravens.

The Lions have struggled defensively in 2025. They rank 18th in points allowed (.389) per play. They’re also giving up 22.4 points per game. Most importantly, the Lions are allowing opponents to score a touchdown on 66.7% of their red zone trips.

This is the type of total that needs touchdowns from both sides. Luckily, these are two of the most aggressive coaches in the NFL in terms of going for it on fourth down. The Chiefs rank fifth and the Lions rank eighth in go-for-it rate this season.

Both offenses are going to need to put points on the board to win this game, and I trust them drastically more than either defense at this point in the season.

Where to Bet: Detroit Lions & Kansas City Chiefs over 52.5 points | +100 at ESPN Bet

2025 NFL Season Betting Record: 7-14