49ers RB Christian McCaffrey listed on injury report with calf issues
Jul 23, 2025; Santa Clara, CA, USA; San Francisco 49ers quarterback Brock Purdy (13) hands off to running back Christian McCaffrey (23) during the first day of training camp at SAP Performance Facility. Mandatory Credit: D. Ross Cameron-Imagn Images The San Francisco 49ers had a surprise addition on their Thursday injury report, listing star running back Christian McCaffrey as being a limited participant with a calf problem.
On-site reporters also reported that McCaffrey was limited.
That was a change from Wednesday's initial report that didn't have McCaffrey listed.
A calf issue cropped up for the three-time Pro Bowler last fall as well, which was eventually diagnosed as an Achilles sprain. That injury caused him to miss the first eight games of the season, then he lost five more games to close the year with a PCL sprain.
McCaffrey finished with career lows in rushing yards (202), rushing touchdowns (zero), receptions (15) and receiving yards (146).
The 49ers open their season Sunday at the Seattle Seahawks.
--Field Level Media
Did the World Baseball Classic Hurt MLB Starting Pitchers?
NBA Picks for March 27: Best Bets for Friday Night Slate
Why St. John's Can Cover Sweet 16 Spread Against Duke
- Why St. John's Can Cover Sweet 16 Spread Against Duke
- MLB Best Betting Picks for Friday March 27th Slate
- Three Sweet 16 Teams To Avoid Betting in March Madness This Weekend
- NBA Betting Picks: Best Bets for Thursday’s Slate
- Why the Nebraska Cornhuskers Have the Edge Against Iowa in Sweet 16
- Ranking the Remaining No. 1 Seeds in March Madness Before Sweet 16
- Best NBA Bets Today: Wednesday Predictions and Player Props

