Photo: Ezra Shaw (Getty)

Buffalo pulled off the biggest upset of the NCAA men’s tournament so far, knocking out fourth-seeded Arizona in a game that became a blowout in the second half.

Things were close throughout the first half, and Arizona almost managed to take a lead into the locker room at halftime. But a three-pointer from Buffalo’s Wes Clark on their final possession of the half put the MAC champion Bulls up by two and from there, they never looked back, cruising to an 89-68 win.

Clark was the leading scorer of the night, with 25 points on 10-of-14 shooting and seven assists.

A fitting end to an Arizona season that saw them tangled in an FBI investigation, battling a report on a major NCAA violation by head coach Sean Miller, and ultimately losing all their recruits.