NFL Week 1 lines: Seahawks, Rams listed as favorites for 2026 openers

The Seattle Seahawks opened as minor favorites for their season-opening Super Bowl LX rematch against the New England Patriots upon the release of the full schedule for the 2026 NFL season Thursday evening.

The Seahawks, who beat the Patriots 29-13 to win their second championship on Feb. 8, open the season against New England on Wednesday, Sept. 9, in Seattle as 3.5- to 4.5-point favorites.

That kicks off a hectic opening week that will see the Los Angeles Rams and San Francisco 49ers face off in Melbourne, Australia, the Giants and Cowboys square off on "Sunday Night Football" and more.

Here is a full list of odds for Week 1 of the 2026 season (all money lines from DraftKings):

Wednesday, Sept. 9

New England Patriots at Seattle Seahawks

8:20 p.m. ET on NBC, Lumen Field, Seattle

Odds: Seahawks -3.5 (DraftKings); -4.5 (FanDuel)

Money line: Seahawks -192; Patriots +160

Total: 44.5 points (DraftKings); 45.5 points (FanDuel)

Thursday, Sept. 10

San Francisco 49ers vs. Los Angeles Rams

8:35 p.m. ET on Netflix, Melbourne Cricket Ground, Melbourne, Australia

Odds: Rams -2.5 (DraftKings and FanDuel)

Money line: Rams -155; Seahawks +130

Total: 48.5 points (DraftKings); 49.5 (FanDuel)

Sunday, Sept. 13

Tampa Bay Buccaneers at Cincinnati Bengals

1 p.m. ET on Fox, Paycor Stadium, Cincinnati

Odds: Bengals -3.5 (DraftKings and FanDuel)

Money line: Bengals -198; Buccaneers +164

Total: 50.5 points (DraftKings); 51.5 points (FanDuel)

Cleveland Browns at Jacksonville Jaguars

1 p.m. ET on CBS, EverBank Stadium, Jacksonville

Odds: Jaguars -7 (DraftKings); -7.5 (FanDuel)

Money line: Jaguars -285; Browns +230

Total: 39.5 points (FanDuel); 40.5 points (DraftKings)

Baltimore Ravens at Indianapolis Colts

1 p.m. ET on CBS, Lucas Oil Stadium, Indianapolis

Odds: Ravens -3.5 (DraftKings and FanDuel)

Money line: Ravens -185; Colts +154

Total: 49.5 points (DraftKings and FanDuel)

New Orleans Saints at Detroit Lions

1 p.m. ET on Fox, Ford Field, Detroit

Odds: Lions -7 (DraftKings and FanDuel)

Money line: Lions -325; Saints +260

Total: 48.5 points (DraftKings and FanDuel)

Atlanta Falcons at Pittsburgh Steelers

1 p.m. ET on Fox, Acrisure Stadium, Pittsburgh

Odds: Steelers -2.5 (FanDuel); -3 (DraftKings)

Money line: Steelers -175; Falcons +145

Total: 41.5 points (FanDuel); 42.5 points (DraftKings)

New York Jets at Tennessee Titans

1 p.m. ET on CBS, Nissan Stadium, Nashville

Odds: Titans -2.5 (FanDuel); -3 (DraftKings)

Money line: Titans -170; Jets +142

Total: 38.5 points (FanDuel); 39.5 points (DraftKings)

Buffalo Bills at Houston Texans

1 p.m. ET on CBS, NRG Stadium, Houston

Odds: Bills -1.5 (DraftKings and FanDuel)

Money line: Bills -112; Texans -108

Total: 44.5 points (FanDuel); 45.5 points (DraftKings)

Chicago Bears at Carolina Panthers

1 p.m. ET on Fox, Bank of America Stadium, Charlotte

Odds: Bears -2.5 (DraftKings and FanDuel)

Money line: Bears -135; Panthers +114

Total: 44.5 points (DraftKings); 45.5 points (FanDuel)

Green Bay Packers at Minnesota Vikings

4:25 p.m. ET on CBS, U.S. Bank Stadium, Minneapolis

Odds: Packers -1.5 (DraftKings and FanDuel)

Money line: Packers -125; Vikings +105

Total: 44.5 points (DraftKings); 46.5 points (FanDuel)

Miami Dolphins at Las Vegas Raiders

4:25 p.m. ET on Fox, Allegiant Stadium, Las Vegas

Odds: Raiders -3 (DraftKings and FanDuel)

Money line: Raiders -180; Dolphins +150

Total: 40.5 points (FanDuel); 41.5 points (DraftKings)

Washington Commanders at Philadelphia Eagles

4:25 p.m. ET on Fox, Lincoln Financial Field, Philadelphia

Odds: Eagles -4.5 (FanDuel); -5.5 (DraftKings)

Money line: Eagles -238; Commanders +195

Total: 46.5 points (DraftKings); 47.5 points (FanDuel)

Arizona Cardinals at Los Angeles Chargers

4:25 p.m. ET on CBS, SoFi Stadium, Inglewood, Calif.

Odds: Chargers -9.5 (FanDuel); -11.5 (DraftKings)

Money line: Chargers -625; Cardinals +455

Total: 45.5 points (DraftKings); 46.5 points (FanDuel)

Dallas Cowboys at New York Giants

8:20 p.m. ET on NBC, MetLife Stadium, East Rutherford, N.J.

Odds: Cowboys -2.5 (DraftKings and FanDuel)

Money line: Cowboys -130; Giants +110

Total: 48.5 points (DraftKings and FanDuel)

Monday, Sept. 14

Denver Broncos at Kansas City Chiefs

8:15 p.m. ET on ESPN, Arrowhead Stadium, Kansas City

Odds: Chiefs -2.5 (DraftKings and FanDuel)

Money line: Chiefs -155; Broncos +130

Total: 42.5 points (DraftKings); 43.5 points (FanDuel)

--Field Level Media